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Redness, swelling, or pus in affected areas are primary indicators of a skin infection. When the skin becomes infected, the body responds with inflammation, which typically manifests as redness and swelling due to increased blood flow to the site to aid in healing. The presence of pus, which consists of dead white blood cells, bacteria, and tissue debris, can also signify that an infection is present. Together, these symptoms indicate a localized response to infection, showing that the body's immune system is actively fighting against pathogens in that area.

Dry patches of skin may indicate other conditions, such as eczema or dermatitis, but they do not specifically suggest an infection. Itchy sensations might arise from various skin issues, including allergies or irritants, and pale skin tone is not necessarily indicative of any infection but could relate to various dermatological or systemic conditions. Thus, the combination of redness, swelling, and the presence of pus serves to confirm a skin infection and is an essential part of recognizing and diagnosing this condition effectively.